11 Early Signs of Childhood Leukemia

11 Early Signs of Childhood Leukemia

Dr. Karuna Kumar

By Dr. Karuna Kumar, MD DNB Hematologist

December 3rd, 2024

Leukemia also known as blood cancer affects our blood and bone marrow, and it is one of the most prevalent cancers in children. While the thought of childhood leukemia can be frightening, recognizing its early signs can lead to faster diagnosis and treatment, which can significantly improve outcomes. We will go over 11 early warning signs of leukemia in children, so parents and caregivers can be more aware and take action when necessary.

What is Childhood Leukemia?

Childhood leukemia affects most of our blood cells, especially white blood cells. In children, leukemia generally falls into two main categories:

Acute Lymphoblastic Leukemia (ALL) is the most prevalent form of leukemia in children.

Acute Myelogenous Leukemia (AML) – Less common, but still a significant type of leukemia in kids.

Leukemia causes abnormal growth of white blood cells, which crowd out normal blood cells and affect the body’s ability to fight infections, control bleeding, and carry oxygen. This results in a variety of symptoms that can mimic other illnesses, so early detection is crucial.

11 Signs of Pediatric Leukemia

1. Pale Skin

One of the first signs of leukemia in children is a pale or unusually light complexion. This happens when there is a reduction in the number of red blood cells, a condition known as anemia. Anemia leads to reduced oxygen supply to the tissues, causing the skin to appear paler than usual. If you notice your child’s skin looks paler than normal, it’s worth considering a medical check-up.

2. Frequent Bruising

Children with leukemia may experience frequent bruising or notice unexplained marks on their skin. This happens because leukemia affects platelets, which are responsible for blood clotting. With fewer platelets, even minor bumps or scrapes can cause bruises that are more severe or happen without any obvious cause.

3. Easy or Unexplained Bleeding

In addition to bruising, leukemia can also cause bleeding problems. Children with leukemia might bleed more easily from their gums or nose. They may experience prolonged or heavier-than-normal bleeding after cuts or scrapes, which is a result of lower platelet levels.

4. Fatigue and Weakness

Children with leukemia often feel unusually tired, weak, or sluggish. Leukemia affects the body’s ability to produce normal red blood cells, which transport oxygen to tissues and muscles. As a result, children may feel tired even after getting enough sleep or may lack the energy to engage in activities they once enjoyed.

5. Frequent Infections or Fever

Leukemia impairs the immune system, making it harder for the body to fight off infections. As a result, children may experience frequent illnesses, such as colds, sore throats, or respiratory infections. Fever is another common sign, often occurring without an obvious infection. Persistent or recurring fever, especially if it is not responding to typical fever-reducing medications, should be taken seriously.

6. Bone or Joint Pain

Another early sign of leukemia is pain in the bones or joints. This occurs when leukemia cells accumulate in the bone marrow, causing swelling and discomfort. Your child may complain of pain in their arms, legs, or joints, especially after physical activity. It can also cause a feeling of stiffness or aching that doesn’t go away.

7. Swelling of the Abdomen or Lymph Nodes

Leukemia can lead to swelling of the spleen and liver, which may cause a noticeable bulge in the abdomen. Lymph nodes, which are part of the immune system, can also become enlarged. If you notice any lumps or swelling in your child’s neck, underarms, or groin, it could be an indication of leukemia or another illness that requires medical attention.

8. Loss of Appetite or Unexplained Weight Loss

Children with leukemia often lose their appetite, which can result in significant weight loss. This can happen because the body is not able to absorb nutrients properly, or because the spleen and liver are swollen, making the child feel full or uncomfortable. Unexplained weight loss is a red flag and should be investigated further.

9. Bleeding Gums 

In addition to skin paleness, children with leukemia may experience bleeding gums, particularly when brushing their teeth. This occurs due to the drop in platelet count, which makes it harder for the body to stop bleeding. If your child’s gums seem unusually sensitive, or if they notice blood in their mouth after brushing, it’s worth mentioning to their pediatrician.

10. Difficulty Breathing

As leukemia progresses, it can interfere with the body’s ability to produce healthy red blood cells. This can cause a shortage of oxygen, leading to shortness of breath or difficulty breathing, even with mild physical activity. If your child seems to be getting winded or tired more easily than usual, it could be a sign that something is wrong with their blood cells.

11. Night Sweats

Night sweats are another common symptom of leukemia. Children with leukemia often wake up to find their clothes or bedding soaked with sweat. These sweats occur as the body tries to fight the cancerous cells or due to an increase in body temperature caused by the disease.

When to Seek Medical Attention?

If your child is showing any combination of the signs mentioned above, it’s important to consult with a healthcare provider as soon as possible. While these symptoms may also be linked to other, less serious conditions, it’s always better to be cautious.

A pediatrician will perform a thorough physical examination and may recommend blood tests to check for leukemia or other health issues. If leukemia is suspected, additional tests, such as a bone marrow biopsy, may be required to confirm the diagnosis.

Conclusion

While leukemia can be difficult to spot in its early stages, knowing the symptoms and keeping an eye out for any of the signs listed above can help with early detection. Timely diagnosis and treatment of leukemia can improve the chances of successful treatment and recovery, so don’t hesitate to seek medical help if you notice any concerning symptoms in your child.

Remember, most of these symptoms can also be caused by other, less serious illnesses. However, if you notice multiple signs appearing together or if the symptoms persist, it’s important to take your child to a doctor. 

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