Bone marrow and stem cell transplant

What is bone marrow?

Bone marrow is the soft, spongy tissue inside your bones that makes blood-forming cells (blood stem cells). These cells turn into blood cells including:

  • White blood cells to fight infections.
  • Red blood cells to carry oxygen throughout the body.
  • Platelets to control bleeding.

Blood-forming cells are also found in the blood stream and the umbilical cord blood.

How does transplant work?

Before transplant, you get chemotherapy (chemo) with or without radiation to destroy the diseased blood-forming cells and marrow. Then, healthy cells are given to you (it’s not surgery). The new cells go into your bloodstream through an intravenous (IV) line, or tube. It’s just like getting blood or medicine through an IV. The cells find their way into your marrow, where they grow and start to make healthy red blood cells, white blood cells and platelets.

What diseases can BMT treat?

Bone marrow transplants can treat:

  • Blood cancers like leukemia or lymphoma
  • Bone marrow diseases like aplastic anemia
  • Other immune system or genetic diseases like sickle cell disease

What are the benefits of stem cell transplants?

  • Stem cell transplants can be used to treat bone marrow conditions that cannot produce healthy blood cells.
  • Transplants are used to replace damaged or destroyed blood cells due to overall cancer treatment.

Stem cell transplants are available for the following conditions:

  • Aplastic anemia severe (bone marrow failure).
  • Leukemia refers to a form of cancer that affects white blood cells.
  • Lymphoma type cancer that affects white blood cells.
  • Myeloma is a form of cancer that affects cells called plasma cells.
  • Certain conditions can cause specific blood, immune, and metabolic disorders. These include sickle cell anemia, thalassemia, severe combined immunodeficiency, SCID, and Hurler syndrome.

A stem cell transplant is usually reserved for patients who have failed to respond to other treatments. The risks exceed the potential benefits of a stem cell transplant.

What are the steps we take in stem cell transplant?

Five main stages are involved in a stem cell transplant. These are:

  • To assess your general health, you may need to have tests and examinations.
  • Harvesting - The process of harvesting stem cells for transplantation, whether from you or a donor.
  • Conditioning - Treatment with radiotherapy and chemotherapy to prepare the body for transplant.
  • Transplantation of stem cells.
  • Recovery.

A stem cell transplant can be a concerted and challenging process. The transplant will take place over some time. Our specialist Dr. Karuna Kumar have years of expertise in treating bone marrow transplant in Hyderabad and are skilled in performing the procedure. He is committed to treating your needs with compassion, and provide you with the highest standard of living. This type of therapy mostly takes up to a year to recover.

frequently asked questions

Is a stem cell transplant and a bone marrow transplant the same thing?

Is a stem cell transplant and a bone marrow transplant the same thing?

The words "bone marrow transplant" and "stem cell transplant" are sometimes used together, which might be confusing. Both names refer to the same procedure. All transplants that used to treat blood or bone marrow cancers contain stem cells.

What is the need for a bone marrow transplant?

What are the reasons for a bone marrow transplant?

Bone marrow transplants replace unhealthy stem cells with healthy ones to cure cancers and other blood and bone marrow disorders. BMT is most often used to treat leukemia and lymphoma patients.

Patients whose bone marrow has been damaged by chemotherapy or radiation treatment may benefit from BMT. It also helps those with conditions that cause their bone marrow to stop working.

Is the process for bone marrow transplantation in children and adults are same?

Is the process for bone marrow transplantation in children and adults are same?

Yes. Irrespective of the patient's age, a bone marrow transplant is generally the same process. For our younger patients, we make certain changes, such as sedating them prior to the transplant to reduce their anxiety.

How long does it take to recover from a bone marrow transplant?

How long does it take to recover from a bone marrow transplant?

Every scenario is different, but most patients should expect to be in the hospital for at least 30 days while their immune system is rebuilt. You will be discharged from the hospital to complete your rehabilitation at home once your doctors feel that your immune system is healthy enough. Your immune function may take several months or years to fully recover following BMT.

Dr. Karuna Kumar is a clinical consultant endowed with Clinical and Academic experience encompassing Hematology, Hematooncology & bone marrow transplantation. Adept at both allogeneic & autologous transplant using bone marrow & peripheral blood stem cells for various benign & malignant conditions, he works deftly during emergency situations with utmost care and responsibility.

Oxy Clinics
Above Sampradaya, West Marredpally, Secunderabad - 500026

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